FUGEN NEZIROGLU is clinical director of the Institute for Bio-Behavioral Therapy and Research (IBBTR) in Great Neck, New York. She is also on the scientific advisory board of the Obsessive Compulsive Foundation. JOSE A. YARYURA-TOBIAS is medical director of IBBTR and a biological psychiatrist and internist who pioneered research in the biological theory of Obsessive Compulsive Disorder.